The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 1996
Filed:
Dec. 15, 1993
David T Curiel, Chapel Hill, NC (US);
Ping-chuan Hu, Chapel Hill, NC (US);
Max L Birnstiel, Vienna, AT;
Matthew Cotten, Vienna, AT;
Ernst Wagner, Langenzersdorf, AT;
Boehringer Ingelheim International, GmbH, South San Francisco, DE;
Genentech, Inc., South San Francisco, CA (US);
University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
Conjugates in which a virus is bound via an antibody to a substance having an affinity for nucleic acid, for transporting gene constructs into higher eucaryotic cells. Complexes of the conjugates and nucleic acid are internalized in the cell, whilst the virus as part of the complex brings about the internalization and the release of the contents of the endosomes, in which the complexes are located after entering the cell. Pharmaceutical preparations in which the nucleic acid is a therapeutically active gene construct, particularly for use in gene therapy.