The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 1996
Filed:
Jan. 11, 1994
Applicant:
Inventors:
Oscar L Acevedo, San Diego, CA (US);
Normand Hebert, San Marcos, CA (US);
Assignee:
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544243 ; 544 35 ; 544102 ; 544104 ; 544242 ; 544262 ; 544264 ; 544267 ; 544277 ; 544298 ; 544309 ; 544311 ; 544313 ; 544314 ; 544317 ; 544335 ; 5483147 ; 5483611 ; 5483615 ; 5483621 ; 5483625 ; 5483641 ; 548412 ; 548413 ; 548440 ; 548441 ; 548443 ; 548444 ; 548446 ; 548465 ; 548466 ; 548467 ; 548518 ; 548519 ; 548523 ; 548524 ; 548530 ; 548531 ; 548542 ; 548546 ;
Abstract
Novel pyrrolidine monomers bearing various functional groups are used to prepare oligomeric structures. The pyrrolidine monomers can be joined via standard phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups include nucleobases as well as polar groups, hydrophobic groups, ionic groups, aromatic groups and/or groups that participate in hydrogen-bonding.
Published as:
CA2180978A1; WO9518792A1; US5519134A; EP0739335A1; EP0739335A4; JPH09509408A; US5714606A; CA2180978C;