The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 1996
Filed:
Sep. 10, 1992
Applicant:
Inventors:
Narasinga Rao, Alameda, CA (US);
Mark B Anderson, Orinda, CA (US);
John J Naleway, Eugene, OR (US);
John H Musser, San Carlos, CA (US);
Assignee:
Glycomed Incorporated, Alameda, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; A01N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514 26 ; 514-2 ; 514 25 ; 514 53 ; 514 54 ; 514 61 ; 514563 ; 536-5 ; 536 172 ; 536 173 ; 536 174 ; 536 175 ; 536 176 ; 536 181 ; 536 221 ; 536 55 ; 536 551 ; 552502 ;
Abstract
Triterpenoid acid derivatives have been found to have structures similar to natural ligands to the extent that these derivatives bind to natural selectin receptors including endothelial leukocyte adhesion molecule-1 (ELAM-1) and leukocyte/endothelial cell adhesion molecule-1 (LECAM-1). The molecules can be administered to the patients by themselves or in pharmaceutical formulations; in order to alleviate inflammation and/or treat other abnormalities associated with the excessive binding of leukocytes to endothelial receptors.