The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 1996

Filed:

Sep. 15, 1993
Applicant:
Inventors:

Leon M Wilkins, Canton, MA (US);

Stephen R Watson, Canton, MA (US);

Assignee:

Organogenesis Inc., Canton, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ;
U.S. Cl.
CPC ...
435-13 ;
Abstract

This invention is directed to cryopreservation of cultured tissue equivalents made by in vitro technology. The invention involves immersing a cultured tissue equivalent in a cooled cryoprotectant solution, agitating the cryoprotectant solution and the immersed cultured tissue to achieve effective penetration of the cryoprotectant solution into the cultured tissue equivalent, and then freezing the cultured tissue at a high freezing rate. The cryopreserved cultured tissue equivalent may be stored for indefinite periods of time prior to use. The cultured tissue equivalent is an in vitro model of the equivalent human tissue, which, when retrieved from storage can be used for transplantation or implantation in vivo or for screening compounds in vitro.


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