The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 1996

Filed:

Aug. 10, 1994
Applicant:
Inventors:

Keun-Ho Lee, Ithaca, NY (US);

Chih-Chang Chu, Ithaca, NY (US);

Jack H Freed, Ithaca, NY (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08G / ;
U.S. Cl.
CPC ...
528320 ; 528310 ; 528335 ; 528354 ; 528361 ; 424-111 ; 424-129 ; 424-133 ; 424-181 ; 424 7808 ; 424 7814 ; 424 7827 ; 424 7829 ;
Abstract

Aminoxyl-containing radical is provided in polymers and copolymers by replacing a hydroxyl moiety in a carboxyl group at a chain end of a starting material biodegradable polymer or copolymer with imino or oxy linked to aminoxyl-containing radical to form an amide linkage or an oxycarbonyl linkage at the chain end of biocompatible polymers or copolymers to the aminoxyl-containing radical. Preferred starting material polymers and copolymers are prepared from the hydroxy alkyl carboxylic acid monomers glycolic acid and lactic acid. Preferred aminoxyl-containing radical is 2,2,6,6-tetramethylpiperidine-1-oxy. Product polymers are useful for aminoxyl-containing radical treatment of tumors, and to increase the efficiency of chemotherapy and ionizing radiation therapy of tumors and for the reconstruction of injured, diseased, or aged human blood vessels.


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