The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 1996

Filed:

Apr. 08, 1994
Applicant:
Inventors:

Donald C Foster, Seattle, WA (US);

Mark J Murray, Seattle, WA (US);

Kathleen L Berkner, Seattle, WA (US);

Assignee:

Zymogenetics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435 681 ; 435 691 ; 4351723 ; 435219 ; 435226 ; 43524025 ; 4353201 ; 536 221 ; 536 231 ; 536 232 ; 536 235 ; 935 14 ; 935 70 ; 935 71 ;
Abstract

Methods are disclosed for producing a protein which has substantially the same biological activity as human protein C or human activated protein C. The protein is produced by mammalian host cells transfected with a plasmid capable of integration in mammalian host cell DNA. The plasmid includes a promoter followed downstream by a nucleotide sequence which encodes a protein having substantially the same structure and/or activity as human protein C or human activated protein C the nucleotide sequence being followed downstream by a polyadenylation signal.


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