The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 1996
Filed:
Oct. 28, 1994
Yoshinori Kyotani, Higashimurayama, JP;
Katsumi Kawamine, Higashimurayama, JP;
Tsutomu Toma, Higashimurayama, JP;
Tadaaki Ohgiya, Higashimurayama, JP;
Takashi Yamaguchi, Urawa, JP;
Kazuhiro Onogi, Iruma, JP;
Seiichi Sato, Tokyo, JP;
Noboru Shimizu, Higashimurayama, JP;
Hiromichi Shigyo, Fuchu, JP;
Tomio Ohta, Sayama, JP;
Toshiaki Oda, Higashimurayama, JP;
Yukihiro Okuno, Higashimurayama, JP;
Kimiyuki Shibuya, Higashimurayama, JP;
Yoshio Takahashi, Iruma, JP;
Mikio Fujii, Iruma, JP;
Yasumi Uchida, Ichikawa, JP;
Kowa Co., Ltd., Nagoya, JP;
Abstract
An indole derivative represented by formula (1), ##STR1## wherein A is a group ##STR2## wherein R.sup.10 is hydrogen or lower alkyl, dotted lines may optionally be present, and R.sup.1 -R.sup.9 represents various substitutional groups. The compound (1) exhibits a positive inotropic action on cardiac muscle, an anti-arrhythmic action, and a vasodilation action without increasing the heart rate. A heart affection therapeutic agent comprising this compound as an effective component is extremely effective for treating heart failures and arrhythmia.