The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 1996
Filed:
Jan. 05, 1994
Applicant:
Inventors:
Joseph D Armstrong, III, Westfield, NJ (US);
Lisa DiMichele, Plainfield, NJ (US);
Alan W Douglas, Monmouth Junction, NJ (US);
Jennifer L Keller, Princeton, NJ (US);
Steven A King, Summit, NJ (US);
Andrew S Thompson, Mountainside, NJ (US);
Thomas R Verhoeven, Cranford, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ; C07C / ;
U.S. Cl.
CPC ...
548543 ; 548482 ; 546216 ; 549346 ; 549356 ; 549429 ; 560115 ; 560151 ; 560179 ; 564186 ; 435-6 ; 540524 ; 540531 ;
Abstract
.beta.- or .gamma.-Ketoesters and .beta.- or .gamma.-ketoamides are asymmetrically reduced with a Ru(II)-BINAP derived catalyst at about 40.degree. C. and about 50N/mm.sup.2 of hydrogen in the presence of a strong acid.