The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 1996

Filed:

Apr. 13, 1992
Applicant:
Inventors:

Robert Zamboni, Point-Claire, CA;

Daniel Guay, Notre Dame De Ile Perrot, CA;

Jacques-Yves Gauthier, Laval, CA;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
5142278 ; 5142315 ; 5142335 ; 5142352 ; 5142358 ; 5142368 ; 5142372 ; 514255 ; 514277 ; 514316 ; 514318 ; 514332 ; 514335 ; 514341 ; 514342 ; 514343 ; 514351 ; 544114 ; 544124 ; 544125 ; 544128 ; 544129 ; 544133 ; 544134 ; 544137 ; 544141 ; 544146 ; 544148 ; 544149 ; 544152 ; 544158 ; 544162 ; 544163 ; 544170 ; 544171 ; 544172 ; 544174 ; 544175 ; 544358 ; 544359 ; 544363 ; 544366 ; 544369 ; 544372 ; 544379 ; 544399 ; 544400 ; 546153 ; 546159 ; 546162 ; 546168 ; 546174 ; 546175 ; 546187 ; 546194 ; 546208 ; 546209 ; 546210 ; 546214 ; 546229 ; 546230 ; 546232 ; 546233 ; 546234 ; 546235 ; 546236 ; 546237 ; 546238 ; 546240 ; 546255 ; 546256 ; 546261 ; 546264 ; 546265 ; 546266 ; 546275 ; 546276 ; 546278 ; 546280 ; 546281 ; 546284 ; 546286 ; 546290 ; 546296 ; 546301 ; 546302 ; 546329 ; 546330 ; 546334 ; 546339 ; 546340 ; 546341 ;
Abstract

Compounds having the formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.


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