The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 1996

Filed:

May. 27, 1994
Applicant:
Inventors:

Robert E Johnston, Chapel Hill, NC (US);

Nancy L Davis, Chapel Hill, NC (US);

Jonathan F Smith, Sabillasville, MD (US);

Franziska B Grieder, Bethesda, MD (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4242181 ; 4352351 ; 435236 ; 536 2372 ; 4241991 ;
Abstract

Novel attenuating mutations of Venezuelan Equine Encephalitis (VEE) are disclosed. Further aspects of the invention include an infectious VEE virus transcript encoded by cDNA clones, infectious VEE virus particles, and pharmaceutical formulations containing such infectious particles. Also disclosed are recombinant VEE virus containing a heterologous RNA segment.


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