The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 1996

Filed:

Jan. 30, 1995
Applicant:
Inventors:

Yasuhiro Kabasawa, Ibaraki, JP;

Fumihiro Ozaki, Ibaraki, JP;

Keiji Ishibashi, Ibaraki, JP;

Takashi Hasegawa, Ibaraki, JP;

Hitoshi Oinuma, Ibaraki, JP;

Toshiaki Ogawa, Ibaraki, JP;

Hideyuki Adachi, Ibaraki, JP;

Hiroshi Katoh, Ibaraki, JP;

Kohtarou Kodama, Ibaraki, JP;

Hideto Ohara, Ibaraki, JP;

Nobuyuki Mori, Ibaraki, JP;

Norio Minami, Ibaraki, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514459 ; 544149 ; 546207 ; 549404 ; 549424 ;
Abstract

The present invention provides a thioformamide derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof, which is highly safe, easy to use, and useful as an excellent hypotensive or heart disease remedy: ##STR1## wherein Y represents ##STR2## or the like [wherein R.sup.7 represents benzyloxy or the like; R.sup.11 and R.sup.12 each represent hydrogen, hydroxyl, benzoyloxy, benzyloxy, ##STR3## (wherein R.sup.14 and R.sup.15 each represent hydrogen, benzyl or the like) or the like]; Z represents --CH.sub.2 -- or the like; A represents imidazolyl or imidazopyridyl which may have one or two substituents, or the like; R.sup.1 and R.sup.2 each represent hydrogen, lower alkyl or the like; and R.sup.3 and R.sup.4 each represent hydrogen, lower alkyl or the like.


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