The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 1996
Filed:
Dec. 28, 1992
Paul Habermann, Taunus, DE;
Friedrich Wengenmayer, Hofheim am Taunus, DE;
Hoechst Aktiengesellschaft, Frankfurt am Main, DE;
Abstract
A fusion protein including a ballast portion and a desired protein. The ballast portion forms either the C- or N-terminus of the fusion protein, and the ballast portion includes a part of the amino acid sequence of interleukin-2 (IL-2). According to certain preferred embodiments, the ballast portion includes approximately the first 100 amino acids of IL-2. According to other preferred embodiments, the ballast portion contains fewer than 100 amino acids of IL-2. According to further advantageous embodiments, a synthetic IL-2 gene is divided by unique cleavage sites into 6 segments, any number of these segments can be linked in arbitrary sequence. These embodiments permit specific instructions with which the solubility of the fusion protein can be altered, and thus the fusion proteins can readily be separated from soluble proteins intrinsic to a host. The DNA coding for the fusion proteins, as well as vectors and hosts are also provided.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile