The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 1996

Filed:

Mar. 29, 1993
Applicant:
Inventors:

Hiromasa Nagao, Kanagawa, JP;

Takashi Yoneya, Tokyo, JP;

Toshio Miyake, Kanagawa, JP;

Atsuo Aoyama, Kanagawa, JP;

Ken-ichi Kai, Kanagawa, JP;

Shun-ichi Kidokoro, Kanagawa, JP;

Yoichiro Miki, Kanagawa, JP;

Kimiko Endo, Tokyo, JP;

Akiyoshi Wada, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12S / ; C12S / ; C12P / ;
U.S. Cl.
CPC ...
435 681 ; 435212 ; 435219 ; 435220 ; 435221 ;
Abstract

A modified protease is disclosed, which is a mutant of the thermostable neutral protease wherein at least one amino acid residue of SEQ ID NO: 1 selected from the group consisting of the 144th leucine residue, the th aspartic acid residue, the 187th glutamic acid residue and the 227th asparagine residues is replaced with an amino acid residue other than said amino acid.


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