The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 1996

Filed:

Jan. 04, 1991
Applicant:
Inventors:

Robert S Hodges, Edmonton, CA;

William Paranchych, Edmonton, CA;

Randall T Irvin, Sherwood Park, CA;

Kok K Lee, Edmonton, CA;

Sastry A Parimi, Edmonton, CA;

Dick E Zoutman, Edmonton, CA;

Peter C Doig, Victoria, CA;

Wah Y Wong, Edmonton, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
4242601 ; 4242421 ; 4241841 ; 4241851 ; 530326 ; 530327 ; 530328 ;
Abstract

A peptide having a sequence corresponding to a C-terminal portion of the Pseudomonas aeruginosa pilin protein is disclosed. The peptide is cross-reactive with surface peptides present in certain bacterial and fungal microorganisms, and is effective in inhibiting binding of such organisms to target epithelial cells. The peptide may also be employed in a vaccine composition, for producing immunity against such cross-reactive microorganisms. Also disclosed are methods of preparing peptides which are cross-reactive with the P. aeruginosa pilin peptide, and chimeric monoclonal antibodies immunoreactive with the pilin peptide.


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