The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 1996

Filed:

Nov. 29, 1994
Applicant:
Inventor:

Srdjan Krstanovic, Windham, NH (US);

Assignee:

Orion Research, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L / ;
U.S. Cl.
CPC ...
422103 ; 422 99 ; 7386108 ; 204604 ; 285911 ; 285342 ; 285343 ; 96106 ;
Abstract

A connectorized capillary and in-line flow cell system which greatly expedites the construction of capillary zone electrophoresis (CZE) and other separation instrumentation. A capillary is mounted within a cavity formed in a body, and a mechanical fastener is positioned about the body. The inner diameter of the fastener is less than the outer diameter of the body, so that the connector may be firmly coupled to any system component having a corresponding portion adapted to accept the fastener. The connectorized capillaries thus permit permanent or semi-permanent attachment to various in-line flow cell devices such as detectors, valves, buffer reservoirs and the like. For example, an in-line conductivity detector is assembled by connecting a conductivity meter to the opposing ends of the flow cell body. Annular sensing surfaces can also be provided within the cell. The same basic flow cell structure can also be used as a discrete separation valve by forming two transverse openings in the flow cell body and by using a ferrule having a slotted or castleated end. The valve can be electrically operated by switching a ground reference electrode between two or more buffer reservoirs. The same connectorized capillaries may also be used with fused plate-type systems containing etched channels.


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