The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 1996
Filed:
Mar. 23, 1994
Applicant:
Inventors:
Richard G Wilde, Newark, DE (US);
Soo S Ko, Wilmington, DE (US);
Jeffrey T Billheimer, West Chester, PA (US);
Assignee:
The Du Pont Merck Pharmaceutical Company, Wilmington, DE (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514336 ; 514252 ; 514256 ; 514365 ; 514374 ; 514397 ; 514406 ; 514422 ; 514431 ; 514432 ; 514443 ; 514450 ; 514456 ; 514459 ; 514469 ; 544333 ; 544405 ; 546268 ; 548204 ; 548236 ; 5483151 ; 5483657 ; 548561 ; 5483111 ; 549-9 ; 549 13 ; 549 23 ; 549 28 ; 549 57 ; 549 58 ; 549355 ; 549397 ; 549401 ; 549425 ; 549463 ; 549467 ; 549 72 ; 549346 ; 549487 ;
Abstract
The present invention provides compounds of Formula I, ##STR1## or a pharmaceutically acceptable salt forms thereof, which are inhibitors of acyl-Coenzyme A: cholesterol O-acyltransferase (ACAT), pharmaceutical compositions containing such compounds, processes for the preparation of such compounds, and the use of such compounds as antihypercholesterolemic and/or antiatherosclerotic agents.