The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 1996
Filed:
Nov. 19, 1993
Applicant:
Inventors:
Robert F Halenbeck, San Rafael, CA (US);
Kirston E Koths, El Cerrito, CA (US);
Joseph W Wrin, San Francisco, CA (US);
Assignee:
Cetus Oncology Corporation, Emeryville, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
435-71 ; 43524027 ; 4351722 ; 435 7021 ; 53038823 ; 5303892 ; 53038815 ;
Abstract
Monoclonal antibodies that bind to an apparent conformational epitope associated with recombinant or native dimeric M-CSF with concomitant neutralization of biological activity, which monoclonal antibodies are substantially unreactive with biologically inactive forms of M-CSF including monomeric and chemically derivatized dimeric M-CSF, are described. Methods of using the antibodies in assays for detection of dimeric M-CSF are also described.