The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 1996
Filed:
Apr. 12, 1993
Applicant:
Inventor:
Thomas M Wilson, Norwich, GB;
Assignee:
Diatech Limited, London, GB;
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4352401 ; 4352523 ; 4352402 ; 4352404 ; 43525233 ; 4353201 ; 536 241 ; 935 34 ; 935 35 ; 935 44 ; 935 66 ;
Abstract
It has been found that the 5' regions of RNA viruses act as enhancers of translation of mRNA. The omega prime (.OMEGA.') sequence of Tobacco Mosaic Virus, derivatives and portions thereof, and 5' leader sequences of other RNA viruses can be ligated upstream of an appropriate mRNA or used in the form of cDNA in an expression vector. The translational enhancers are effective in many different types of expression system, for example plant cells, bacteria, and animal cells, and also in in vitro translation.