The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 1996
Filed:
Apr. 19, 1994
Dennis P Orgill, Belmont, MA (US);
Charles E Butler, Brookline, MA (US);
Mark Barlow, Boston, MA (US);
Scott Ritterbush, Saugus, MA (US);
Ioannis V Yannas, Newton, MA (US);
Carolyn C Compton, Chestnut Hill, MA (US);
Brigham & Women's Hospital, Boston, MA (US);
Shriners Hospital for Crippled Children, Tampa, FL (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Integra LifeSciences, Corporation, Plainsboro, NJ (US);
Abstract
The present invention relates to a method of skin regeneration of a wound or burn in an animal or human. This method comprises the steps of initially covering the wound with a collagen glycosaminoglycan matrix, allowing infiltration of the grafted GC matrix by mesenchymal cells and blood vessels from healthy underlying tissue and applying a cultured epithelial autograft sheet grown from epidermal cells taken from the animal or human at a wound free site on the animal's or human's body surface. The resulting graft has excellent take rates and has the appearance, growth, maturation and differentiation of normal skin.