The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 1996
Filed:
Mar. 06, 1995
Applicant:
Inventors:
Eileen R Mulvihill, Seattle, WA (US);
Shinji Yoshitake, Ibaraki, JP;
Yasunori Ikeda, Ibaraki, JP;
Suguru Suzuki, Ibaraki, JP;
Akira Hashimoto, Ibaraki, JP;
Teruaki Yuzuriha, Ibaraki, JP;
Bjorn A Nexo, Soborg, DK;
Assignee:
ZymoGenetics, Inc., Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
435226 ; 124 9464 ; 435 712 ; 4352402 ; 4352523 ; 43525231 ; 43525233 ; 43525411 ; 43525421 ; 4352543 ; 4353201 ; 536 232 ;
Abstract
Tissue plasminogen activator analogs containing the growth factor domain of native t-PA, the domain having at least one cysteine residue replaced with another amino acid. The t-PA analogs may further contain a variety of substitutions and/or modifications. Pharmaceutical compositions containing one or more of the t-PA analogs along With a physiologically acceptable carrier or diluent are also disclosed.