The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 1996

Filed:

Sep. 02, 1993
Applicant:
Inventors:

Malcolm E Kenney, Cleveland Heights, OH (US);

Nancy L Oleinick, University Heights, OH (US);

Boris D Rihter, Wauwatosa, WI (US);

Ying-Syi Li, Cleveland Heights, OH (US);

Assignee:

University Hospitals of Cleveland, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C09B / ; C09B / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514 63 ; 514 43 ; 514185 ; 514191 ; 536 2911 ; 540123 ; 540125 ; 540128 ; 540140 ;
Abstract

The present invention relates to a series of novel phthalocyanine compositions (or compounds) suitable for use as photosensitizers for photodynamic therapy. Specifically, the invention relates to a series of new aluminum (Al) germanium (Ge), gallium (Ga), tin (Sn) and/or silicon (Si) phthalocyanines having substituted amine or quaternary ammonium axial ligands attached to the central metal, and the use of these new phthalocyanine compositions for the treatment of cancer through photosensitization. Moreover, the present invention is directed to the methods of preparing these compositions for use in photodynamic therapy.


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