The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 1996

Filed:

Jan. 06, 1995
Applicant:
Inventors:

Won T Cho, Cheongju, KR;

Wan S Kim, Seoul, KR;

Myung K Kim, Seoul, KR;

Jin K Park, Seoul, KR;

Hak R Kim, Seoul, KR;

Sang K Rhee, Seoul, KR;

A G Domracheva, Moscow, RU;

T B Panichkina, Moscow, RU;

L A Saburoba, Moscow, RU;

L M Nobikoba, Moscow, RU;

Y E Bartochevichi, Moscow, RU;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C12N / ; C12P / ;
U.S. Cl.
CPC ...
435 78 ; 43525235 ; 435886 ; 536-64 ;
Abstract

Disclosed herein are a novel strain of Streptomyces and a method for the production of aclacinomycins A, B, Y and aglycone thereof by cultivating the same. Streptomyces lavendofoliae DKRS(KCTC 0092BP) of the present invention is capable of producing aclacinomycins A, B, Y and aglycone with higher yield. Further, it is possible to selectively produce aclacinomycin A or Y by adjusting pH of the cultured broth of Streptomyces lavendofoliae DKRS to 4.4 or 4.6 with acetate buffer or hydrochloric acid, respectively.


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