The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 1996
Filed:
Nov. 14, 1994
Applicant:
Inventors:
Kent A Berryman, Ann Arbor, MI (US);
Amy M Bunker, Ypsilanti, MI (US);
Annette M Doherty, Ann Arbor, MI (US);
Jeremy J Edmunds, Ypsilanti, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514414 ; 514 64 ; 514 80 ; 514381 ; 514382 ; 514418 ; 548250 ; 548251 ; 548252 ; 548253 ; 548405 ; 548412 ; 548454 ; 548484 ; 548485 ; 548486 ; 548490 ; 548491 ; 548492 ; 548503 ; 548504 ; 548506 ; 548507 ; 548511 ;
Abstract
Novel indole and indoline nonpeptide antagonists of endothelin I are described, as well as novel intermediates used in their preparation, methods for the preparation and pharmaceutical compositions of the same, which are useful in treating elevated levels of endothelin, essential renovascular malignant and pulmonary hypertension, cerebral infarction, cerebral ischemia, congestive heart failure and subarachnoid hemorrhage.