The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 1996
Filed:
Dec. 13, 1994
Applicant:
Inventors:
Ping Chen, Lawrenceville, NJ (US);
Peter T Cheng, Lawrenceville, NJ (US);
Steven H Spergel, Bensalem, PA (US);
Joel C Barrish, Holland, PA (US);
John K Thottathil, Robbinsville, NJ (US);
Robert Zahler, Pennington, NJ (US);
Richard P Polniaszek, South Brunswick, NJ (US);
Xuebao Wang, East Brunswick, NJ (US);
Assignee:
Bristol-Myers Squibb Company, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
549514 ; 560160 ;
Abstract
The present invention relates to a novel method useful for the conversion of amino acids to halomethylketones, which are then converted to amino acid epoxides. Such epoxides are important intermediates for the synthesis of inhibitors of renin and HIV protease, which are particularly useful in the treatment and/or prevention of HIV infection (AIDS).