The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 1995
Filed:
May. 29, 1992
Applicant:
Inventors:
C Anne Higley, Newark, DE (US);
Ruth R Wexler, Wilmington, DE (US);
Richard G Wilde, New Castle, DE (US);
Assignee:
The Du Pont Merck Pharmaceutical Company, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514258 ; 544262 ; 544264 ; 544276 ; 544277 ; 544271 ; 544272 ; 546118 ; 546119 ;
Abstract
This invention relates to pyrazolo pyrimidines for the treatment of atherosclerosis as inhibitors of acyl--CoA, cholesterol acyetransferase (ACAT), and their use as antihypercholesterolemic agents, pharmaceutical compositions and preparation, and having the formula (I): ##STR1## wherein: A and Q are selected independently from CH or N with no more than two nitrogens per ring: