The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 1995
Filed:
May. 10, 1991
Genevieve Pussard nee Contant, Courbevoie, FR;
Jean-Luc Martinolli, Villeneuve la Garenne, FR;
Gerad Quentin, Colombes, FR;
Serbio, , FR;
Abstract
The present invention relates to the use of a substance which inhibits the plasma proteins .alpha..sub.2 -AP and/or .alpha..sub.2 -M in the field of the determination and assay of plasminogen activators and inhibitors of said plasminogen activators. It relates in particular to a method of determining (i) a plasminogen activator selected from the group consisting of tissue plasminogen activators (tPAs) and urokinase plasminogen activators (uPAs), and (ii) an inhibitor (PAI) of said plasminogen activator, said method, which involves converting plasminogen to plasmin and then assaying the plasmin resulting from said conversion, comprising inhibition of the plasma proteins .alpha..sub.2 -antiplasmin and/or .alpha..sub.2 -macroglobulin by means of a substance selected from the group consisting of metalloproteinase materials.