The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 1995
Filed:
Sep. 29, 1993
Applicant:
Inventor:
Eugene Roberts, Monrovia, CA (US);
Assignee:
City of Hope, Duarte, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
530330 ;
Abstract
Three non-amnestic and non-memory enhancing peptides, Asp Phe Phe Val Gly (SEQ ID NO: 1), Gln Phe Val Gly (SEQ ID NO: 2), and Ala Ile Phe Thr (SEQ ID NO: 3), that block the effects of .beta.-(12-28), a peptide homologous to amyloid .beta. protein (A.beta.) are disclosed. This invention relates to amelioration of amnesia and other neurotoxicitiy in Alzheimer disease (AD) caused by deposition of A.beta. and, therefore, relates to attenuation of the disease process and consequential improvement of the quality of life for individuals suffering from AD.