The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 1995
Filed:
Nov. 25, 1992
Applicant:
Inventors:
Marcia L Dawson, Menlo Park, CA (US);
James F Cameron, Palo Alto, CA (US);
Peter D Hobbs, Moss Beach, CA (US);
Ling Jong, Sunnyvale, CA (US);
Magnus Pfahl, Solana Beach, CA (US);
Xiao-kun Zhang, La Jolla, CA (US);
Jurgen M Lehmann, Solana Beach, CA (US);
Assignees:
SRI International, Menlo Park, CA (US);
La Jolla Cancer Research Foundation, La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ;
U.S. Cl.
CPC ...
560100 ; 562490 ;
Abstract
Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.