The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 1995
Filed:
Mar. 31, 1993
Applicant:
Inventors:
Robert Mierendorf, Madison, WI (US);
Richard Garber, Seattle, WA (US);
Robert Novy, Verona, WI (US);
Beth Hammer, Madison, WI (US);
Assignee:
Novagen, Inc., Madison, WI (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12N / ; C12P / ;
U.S. Cl.
CPC ...
435-6 ; 435-71 ; 435 9141 ; 4351723 ; 435 691 ; 4353201 ; 4352523 ; 935 77 ; 935 23 ; 935 79 ; 935 80 ; 436501 ;
Abstract
A method for determining the nucleic acid sequence that encodes ligand binding domain on any protein encoded by a known gene includes the steps of non-specifically cleaving the coding region of the known gene, size-selecting the cleavage products, cloning the size-selected gene products into an expression vector active in a heterologous host, using a novel cloning strategy expressing the peptides produced by the clones and screening for clones that produce peptides that interact with an antibody or ligand of interest.