The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 1995

Filed:

Apr. 28, 1994
Applicant:
Inventors:

Hiroshi Matoba, Osaka, JP;

Shinji Ohmori, Ikeda, JP;

Hiroyoshi Koyama, Mishima, JP;

Toshio Kashihara, Suita, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424 781 ; 424 7816 ; 424 7811 ; 514974 ;
Abstract

(A) A clad powdery or granular preparation of a medicinally active ingredient and (B) a powdery or granular ion exchanger such as a cation exchange resin are blended to prepare a solid preparation. The active ingredient includes .beta.-lactam antibiotics having a basic group. The clad powdery or granular preparation includes not only coated preparation wherein the active ingredient or preparation is coated but also a variety of preparations in which the contact of the active ingredient with the ion exchanger is suppressed or inhibited. Polymers such as a water-soluble polymer, an enteric polymer and so on can be used as the coating agent for the coated preparation. The using amount of the ion exchanger is about 10 to 5,000 parts by weight per 100 parts by weight of the active ingredient. Said solid preparation can remarkably decrease the unpleasant taste and odor of the active ingredient such as bitterness, being excellent in dissolution property and absorbability of the active ingredient.


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