The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 1995
Filed:
Nov. 01, 1994
Applicant:
Inventors:
S Richard Baker, Indianapolis, IN (US);
Robert D Dillard, Zionsville, IN (US);
Paul E Floreancig, Mountain View, CA (US);
J Scott Sawyer, Indianapolis, IN (US);
Michael J Sofia, Carmel, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514381 ; 514 13 ; 514 14 ; 514 15 ; 514 16 ; 514 17 ; 514 18 ; 514 19 ; 514252 ; 514318 ; 514332 ; 514340 ; 514343 ; 514346 ; 514347 ; 514351 ; 514521 ; 514520 ; 514570 ; 5142395 ; 5142392 ; 5142388 ; 5142378 ; 5142335 ; 5142328 ; 548250 ; 548252 ; 562463 ; 562466 ; 562469 ; 562471 ;
Abstract
Antagonists having a substituted phenyl phenol or a substituted phenolic biphenyl structure, and various derivatives thereof, are specific leukotriene antagonists. Their structures, use and synthesis are disclosed. Also, pharmaceutical formulations are disclosed for use in applications treating diseases or conditions characterized by excessive release of leukotriene B.sub.4, one of the metabolites of arachidonic acid. The primary LTB.sub.4 antagonistic structures are represented as: ##STR1##