The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 1995
Filed:
Aug. 11, 1993
Applicant:
Inventors:
Murray A Kaplan, Syracuse, NY (US);
Lawan Phusanti, Lafayette, NY (US);
Robert K Perrone, Liverpool, NY (US);
Scott R Stenberg, Baldwinsville, NY (US);
Sheeram Agharkar, Fayetteville, NY (US);
Joseph B Bogardus, Manlius, NY (US);
Assignee:
Bristol-Myers Squibb Co., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07F / ;
U.S. Cl.
CPC ...
514492 ; 556137 ;
Abstract
Solutions of carboplatin and other malonato platinum(II) antitumor agents are prepared containing stabilizing amounts of 1,1-cyclobutanedicarboxylic acid or salt at pH 4-8. The stabilizers inhibit unacceptable discoloration and precipitation. The solutions may also be stabilized by purging the carrier with air or oxygen and, optionally, blanketing the headspace with air or oxygen.