The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 1995
Filed:
Aug. 16, 1993
Shu-Ching Ma, Burlington, MA (US);
Mark E Meyerhoff, Ann Arbor, MI (US);
Victor C Yang, Ann Arbor, MI (US);
The Board of Regents of the University of Michigan, Ann Arbor, MI (US);
Abstract
An anion exchange membrane for ionic macromolecules, specifically heparin, which is formed of a polymeric matrix material and an anion exchange material suitable for heparin detection can be employed in an electrochemical sensor arrangement to directly measure the concentration of heparin ions in blood or blood fluid. Potentiometric response to heparin has been observed with membranes comprising 30-70 wt. % polymeric matrix material, such as polyvinyl chloride, 0.1-12 wt. % quaternary ammonium salt, such as tridodecyl methyl ammonium chloride, and 30-70 wt. % of a plasticizer, such as dioctyl sebacate. Moreover, a solid state sensor employs tridodecyl methyl ammonium chloride (TDMAC) dissolved in a polymeric compound, such as silicone rubber, to form a membrane which is responsive to heparin concentration.