The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 1995

Filed:

Dec. 29, 1992
Applicant:
Inventors:

John W Ullrich, Philadelphia, PA (US);

Terence J Kiesow, Pottstown, PA (US);

Kent W Neuenschwander, Schwenksville, PA (US);

Keith S Learn, Perkiomenville, PA (US);

William P Dankulich, Collegeville, PA (US);

Anthony C Scotese, King of Prussia, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514375 ; 548217 ; 548219 ; 548156 ; 548169 ; 548235 ; 548478 ; 546176 ; 549 55 ; 549362 ; 549440 ; 549407 ; 544238 ;
Abstract

This invention relates to a class of novel polycyclic compounds containing a cycloalkyl ring having substituted thereon a primary amine and which is further linked or bridged to two mono- and/or bicyclic rings and which reduces levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.


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