The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 1995

Filed:

Oct. 14, 1994
Applicant:
Inventor:

Steven F Ziegler, Seattle, WA (US);

Assignee:

Immunex Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4352401 ; 4352523 ; 43525411 ; 4353201 ; 435194 ; 536 232 ; 536 235 ;
Abstract

A novel receptor protein tyrosine kinase named ork (orphan receptor tyrosine kinase) is identified and characterized. cDNA encoding the ork protein is inserted into an expression vector for production of the protein via recombinant DNA technology. The ork cDNA, when transfected into Cos-7 cells, encodes a 140 Kd protein with in vitro kinase activity. The ork gene is expressed predominantly in placenta and lung, with lower levels in umbilical vein endothelial cells, brain and kidney.


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