The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 1995

Filed:

Jan. 13, 1994
Applicant:
Inventors:

Lothar Zenker, Radebeul, DE;

Helmut Wunderlich, Dresden, DE;

Dieter Lohmann, Radebeul, DE;

Angelika Rostock, Dresden, DE;

Christine Siegemund, Weinbohla, DE;

Artur V Valdman, Moskau, SU;

Tatjana A Voronina, Moskau, SU;

Ilmira C Rachmankulova, Moskau, SU;

Oleg M Glozman, Moskau, SU;

Taisija L Garibova, Moskau, SU;

Larisa M Mescerjakova, Moskau, SU;

Ljudmila A Zmurenko, Moskau, SU;

Sergej B Seredenin, Moskau, SU;

Grigorij G Rozancev, Moskau, SU;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514343 ; 514423 ; 514340 ; 514408 ; 546268 ; 546275 ; 546281 ; 548530 ; 548539 ; 548540 ;
Abstract

The invention is directed to N-acetyl-4-phenyl-pyrrolidin-2-ones, which, because of their pronounced cerebroprotective effect in human medicine, can be used for the prophylaxis and treatment of cerebral functional disorders. Pursuant to the invention, these compounds are synthesized by reacting 4-phenyl-pyrrolidin-2-ones with a reactive derivative of a carboxylic acid, or by cyclizing N-acylaminobutyric acid derivatives.


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