The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 1995

Filed:

Jan. 05, 1994
Applicant:
Inventors:

Vittorio Vecchietti, Milan, IT;

Giulio Dondio, Milan, IT;

Silvano Ronzoni, Milan, IT;

Roberto Colle, Basiglio, IT;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514250 ; 514280 ; 514283 ; 514285 ; 544343 ; 546 49 ; 546 53 ; 546 54 ; 546 56 ; 546 57 ; 546 62 ; 546 70 ;
Abstract

##STR1## Compounds of formula (I) in which, R is linear or branched alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, aryl, aralkyl or furan-2-yl alkyl; R.sub.1 and R.sub.2, which may be the same or different, are each hydrogen, hydroxy, alkoxy, or halogen; R.sub.3 is hydrogen, hydroxy or alkoxy; 'Het' is optionally substituted single or fused heteroxyclic ring, containing from 5 to 10 ring atoms and comprising up to four heteratoms in the or each ring, selected from oxygen, nitrogen and sulphur; R.sub.4 and R.sub.5, which may be the same or different, are each hydrogen alkyl, halogen, nitro; CF, cyano, alkoxy carbonyl, NH, alkylcarbonylamino, hydroxy, alkoxy, or benzyl, are selective delta receptor agonists and are useful in the treatment of pain.


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