The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 1995
Filed:
May. 08, 1992
Ben K Seon, Williamsville, NY (US);
Health Research, Inc., Buffalo, NY (US);
Abstract
A leukemia lymphoma reactive monoclonal antibody which, relative to normal peripheral blood cells, strongly reacts with one or more leukemia lymphoma cell specimens selected from the group consisting of B non-Hodgkin's lymphoma cells, B chronic lymphocytic leukemia cells, B prolymphocytic leukemia cells, B hairy cell leukemia cells, and B acute lymphoblastic leukemia cells. More specifically, a novel hybrid cell line, designated 2B-4G9, for production of monoclonal antibody specific for a unique cell surface epitope associated with a wide variety of human lymphomas and leukemias is provided. This invention also provides a method for producing the new monoclonal antibody and to diagnostic procedures using the new monoclonal antibody to detect various leukemias and lymphomas. Also disclosed are methods of using the antibody or reactive fragments of the antibody for the treatment of leukemia-lymphoma patients.