The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 1995
Filed:
Sep. 18, 1992
Applicant:
Inventors:
Anthony K Cheng, Brea, CA (US);
Thomas S Dobashi, Rosemead, CA (US);
Assignee:
Beckman Instruments, Inc., Fullerton, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; G01N / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
530405 ; 530362 ; 530363 ; 530367 ; 530400 ; 530403 ; 530406 ; 436543 ; 562553 ; 562590 ;
Abstract
A method for making a valproic acid derivative comprising a functionalized spacer arm attached to a .delta. carbon atom of a valproic acid molecule is disclosed. The method proceeds by attaching a spacer arm joined to an inorganic moiety to a valproic acid precursor to make an alkylated compound, derivatizing the alkylated compound in a liquid medium to make the valproic acid derivative, and then separating the valproic acid derivative from the liquid medium. The valproic acid derivative can be used to make an immunoreactive valproic acid conjugate.