The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 1995

Filed:

Oct. 21, 1993
Applicant:
Inventors:

James Blake, Seattle, WA (US);

Carol-Ann Cole, Seattle, WA (US);

Patrick F Coleman, Edmonds, WA (US);

Nobuo Monji, Seattle, WA (US);

John P Montana, Montlake Terrace, WA (US);

Assignee:

Genetic Systems Corporation, Redmond, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ;
U.S. Cl.
CPC ...
435-5 ; 435-792 ; 435974 ; 436518 ; 436531 ; 530317 ; 530324 ; 530334 ; 530336 ; 530345 ; 530402 ; 530403 ; 530404 ;
Abstract

Peptides immunoreactive with antibodies to native proteins, and which have at least two cysteine residues that contribute to mimicking an epitope of the protein, are prepared with the cysteine thiol groups protected. When deprotected, the peptides have enhanced immunoreactivity. The peptides are particularly useful for detecting antibodies or antigens associated with retroviruses, including the clinically important lymphotropic retroviruses HIV-1, HIV-2, HTLV-I, and HTLV-II.


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