The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 1995
Filed:
Nov. 17, 1993
Applicant:
Inventors:
Clifford W Sachs, Durham, NC (US);
Robert L Fine, Durham, NC (US);
Lawrence M Ballas, Apex, NC (US);
R Ivy Carroll, Durham, NC (US);
Robert Bell, Durham, NC (US);
Assignees:
Research Triangle Institute Duke University, Research Triangle Park, NC (US);
Pharmaceuticals Corporation, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
5142318 ; 5142375 ; 5142395 ; 514252 ; 514255 ; 514316 ; 514319 ; 514325 ; 514649 ; 544 79 ; 544156 ; 544357 ; 544380 ; 546191 ; 546204 ; 552247 ; 552255 ;
Abstract
Potentiating agents inhibit the development of multidrug resistance, reduce drug-resistance in drug-resistant tumors, or sensitize tumors to antineoplastic drugs, thereby potentiating the effect of antineoplastic agents. The potentiating agents are aminoanthraquinones, preferably 1,4-bis(N-substituted) amino anthraquinones, and pharmaceutically acceptable salts thereof.