The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 1995
Filed:
Dec. 17, 1993
Shuji Takahashi, Tokyo, JP;
Masaaki Takahashi, Tokyo, JP;
Kazuhiko Tanzawa, Tokyo, JP;
Kaneo Ogawa, Iwaki, JP;
Tsuyoshi Hosoya, Tsukuba, JP;
Sankyo Company, Limited, Tokyo, JP;
Abstract
Compounds of formula (I): ##STR1## (wherein R represents a hydrogen atom or an acetyl group), which we have named 'the adenophostins', and, have the ability to increase intracellular calcium ion concentrations by acting on the inositol 1,4,5-trisphosphate (InsP.sub.3) receptors which exist in the endoplasmic reticulum. The adenophostins are useful as hypertensive agents. They can be prepared by cultivation of a microorganism of the genus Penicillium, e.g. Penicillium brevicompactum SANK 11991 (FERM BP-3499) or Penicillium brevicompactum SANK 12177 (FERM BP-3500).