The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 1995
Filed:
Jun. 15, 1993
Applicant:
Inventors:
Nobuyuki Fukazawa, Mobara, JP;
Tuneji Suzuki, Mobara, JP;
Kengo Otsuka, Mobara, JP;
Osamu Yano, Mobara, JP;
Daiji Iwata, Mobara, JP;
Yukichi Kawai, Mobara, JP;
Assignee:
Mitsui Toatsu Chemicals, Incorporated, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514253 ; 544363 ;
Abstract
Compounds having an activity to stimulate the carcinostatic effect of carcinostatic agents, which can be expressed by the following general formula (1): ##STR1## in which A is ##STR2## (in which R.sub.1, R.sub.2 and R.sub.3 are each independent and represent a hydrogen atom or a phenyl group) are made into fumarates so as to improve their oral absorbability and solubility in water without interfering with their effects.