The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 1995
Filed:
Aug. 13, 1992
Applicant:
Inventors:
Anders Grubb, Lund, SE;
Ake Lundwall, Lund, SE;
Magnus Abrahamson, Lund, SE;
Henrik Dalboge, Virum, DK;
Assignee:
Novo Nordisk A/S, Bagsvaerd, DK;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07K / ;
U.S. Cl.
CPC ...
530350 ; 435 692 ;
Abstract
A recombinant cystatin C polypeptide or a derivative thereof, such as 3-des-hydroxy-cystatin C, is produced biosynthetically by fermentation of a microorganism into which plasmids containing a DNA-sequence coding for said polypeptide have been introduced. Preparations containing recombinant cystatin C, preferably 3-des-hydroxy-cystatin C, have a higher cystein proteinase inhibitor activity than native cystatin C, isolated from human fluids. Such preparations are useful in therapeutic treatments of patients suffering from different diseases, for example herbes simplex.