The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 1995
Filed:
Apr. 09, 1993
Applicant:
Inventors:
Jean-Claude Pascal, Cachan, FR;
Gary McCort, Paris, FR;
Dominique Blondet, Paris, FR;
Francoise Gellibert, Cachan, FR;
Assignee:
Syntex Pharmaceuticals, Ltd., Maidenhead, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514252 ; 514241 ; 514318 ; 514326 ; 544180 ; 544217 ; 544219 ; 544295 ; 544360 ; 544364 ; 544369 ; 544370 ; 544372 ; 544379 ; 546194 ; 546207 ; 546208 ; 546209 ; 546210 ; 546213 ; 546214 ; 514241 ; 514318 ; 514326 ;
Abstract
Compounds of the formula: ##STR1## wherein A, R.sup.1, R.sup.2, R.sup.3 and m are defined as in the specification or a pharmaceutically acceptable acid addition salt or N-oxide thereof, are calcium and sodium channel antagonists useful for treating mammals having a variety of disease states, such as stroke, epilepsy, hypertension, angina, migraine, arrhythmia, thrombosis, embolism, and also for treatment of spinal injuries.