The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 1995
Filed:
Jul. 24, 1992
Applicant:
Inventors:
Thomas Zimmermann, Naters, CH;
Karen Robins, Visp, CH;
Olwen M Birch, Naters, CH;
Elisabeth Bohlen, Naters, CH;
Assignee:
Lonza Ltd., Gampel/Valais, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435129 ; 435195 ; 4353201 ; 43525233 ; 4352523 ; 536 232 ;
Abstract
A genetic engineering process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide. For this purpose, a new DNA is isolated from a microorganism that codes for a stereospecific hydrolase. This DNA is then ligated in an expression vector, and a hybrid plasmid results, which is transformed into microorganisms. These microorganisms are then able to biotransform the R-(-) isomer in racemic R,S-(.+-.)-2,2-dimethylcyclopropanecarboxamide into R-(-)-2,2-dimethylcyclopropanecarboxylic acid, and optionally active S-(+)-2,2-dimethylcyclopropanecarboxamide is obtained.