The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 1995
Filed:
Apr. 28, 1994
Nan-Horng Lin, Mundelein, IL (US);
Yun He, Milwaukee, WI (US);
Richard L Elliott, Grayslake, IL (US);
Mukund S Chorghade, Gurnee, IL (US);
Thomas K Esch, Hohentengen, DE;
Dieter O Beer, Waldshut-Tiengen, DE;
Christian C Witzig, Zurich, CH;
Thomas C Herzig, Oberentfelden, CH;
Steven J Wittenberger, Mundelein, IL (US);
William H Bunnelle, Mundelein, IL (US);
Bikshandar A Narayanan, Mundelein, IL (US);
Pulla R Singam, Waukegan, IL (US);
Alla V Rama Rao, Hyderabad, IN;
Abbott Laboratories, Abbott Park, IL (US);
Abstract
A novel process for preparing enantiomerically-pure 3-methyl-5-(1-(C.sub.1 -C.sub.3 -alkyl)-2-pyrrolidinyl)isoxazole in high yield, wherein a protected pyrrolidine or 2-oxo-pyrrolidine starting material is reacted with a suitable organic anion and a resulting beta-keto oxime intermediate is cyclized and dehydrated, as well as intermediates useful in the preparation thereof.