The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 1995

Filed:

Feb. 01, 1993
Applicant:
Inventors:

Hua-Pin Huang, Succasunna, NJ (US);

Scott C Wootton, Liberty Corner, NJ (US);

Thomas N Julian, Annandale, NJ (US);

Galen W Radebaugh, Chester, NJ (US);

Mahdi B Fawzi, Flanders, NJ (US);

Assignee:

Warner-Lambert Company, Morris Plains, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514 60 ; 514 54 ; 514333 ; 514334 ; 514335 ; 514357 ; 514778 ; 514879 ; 514960 ; 514970 ; 514972 ;
Abstract

Solid compositions of certain cholinergic compounds are stabilized in starch. Especially compositions of corn starch combined or mixed with the 0-substituted-1,2,5,6-tetrahydro-3-pyridine oxime ether, CI-979 HCl, a cognition activator, have been found stable in a heated environment of up to 60.degree. C. over 17 days such that no losses were detected by HPLC analysis. A solid peroral pharmaceutical formulation for the treatment of cognitive disorders is based on the bicomponent composition of active ingredient and stabilizer using appropriate amounts of other excipients or components known in the formulation art.


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