The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 1995

Filed:

Dec. 16, 1991
Applicant:
Inventors:

Sheo B Singh, Edison, NJ (US);

Gerald F Bills, Roselle, NJ (US);

Russell B Lingham, Watchung, NJ (US);

Keith C Silverman, Somerset, NJ (US);

Deborah L Zink, Manalapan, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514452 ; 549261 ; 549413 ; 549477 ;
Abstract

This invention relates to pharmaceutical compounds of structural formulae (I) and (II): ##STR1## and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.


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