The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 1995
Filed:
Mar. 19, 1993
Applicant:
Inventors:
Daljit S Dhanoa, Secaucus, NJ (US);
Kenneth J Fitch, Cranford, NJ (US);
Daniel F Veber, Ambler, PA (US);
Thomas F Walsh, Watchung, NJ (US);
David L Williams, Jr, Telford, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A01N / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514256 ; 5142295 ; 5142305 ; 514247 ; 514258 ; 514269 ; 514826 ; 514893 ; 544242 ; 544245 ; 544253 ; 544283 ; 544295 ; 544298 ; 544299 ; 544300 ; 544301 ; 544302 ; 544304 ; 544305 ; 544309 ; 544310 ; 544311 ; 548100 ; 548124 ; 548146 ; 548181 ; 548182 ; 548184 ; 548190 ;
Abstract
Phenoxyphenylacetic acids and derivatives of general structural formula I ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, inflammatory diseases, Raynaud's disease, and endotoxic shock, and asthma.